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Depakote Problems

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mdw1000

Junior Member
What is the name of your state? Michigan.

Is anyone here aware of any problems or litigation related to the use of Depakote, and in particular bone marrow suppression caused by the use of Depakote?
 


rmet4nzkx

Senior Member
mdw1000 said:
What is the name of your state? Michigan.

Is anyone here aware of any problems or litigation related to the use of Depakote, and in particular bone marrow suppression caused by the use of Depakote?
That is a known contra indication for the use of Carbamazepine Carbatrol®; Epitol®; Tegretol®; Tegretol®-XR but not Depakote, have you taken other ASDs in the past, what current and past Rx? For what disorder?
 

ellencee

Senior Member
Depakote is known for suppression of bone marrow and a variety of other hematologic adverse effects such as: lymphocytosis, thrombocytopenia, leukopenia, eosinophilia, anemia, hypofibrinogenemia, and altered bleeding time; all of which are related to the body's production of blood cells in the bone marrow.

It is important for patients receiving Depakote to have baseline blood analysis prior to beginning Depakote and to have the therapeutic level of Depakote monitored routinely and for the patient's bloodwork to be monitored routinely for signs of decreases in platelets and other blood cells. If bone marrow suppression or other blood cell disorders are identified, Depakote should be discontinued and alternate medication pursued.

As for any litigation regarding bone marrow suppression, I doubt any class actions suits exists as the drug company has never denied the potential risk of bone marrow suppression or denied the more serious adverse effects on the liver. It is up to the physician to monitor the patient receiving Depakote and to know which patients should NEVER receive Depakote (children <18 months, pregnant women or nursing mothers, persons with hepatic disease). I will search for any class action suits, though, if you'll tell us why you asked.
EC
 
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rmet4nzkx

Senior Member
This question has been sitting around unaswered for over 3 months until Geisterhund brought it up, so I doubt is OP will come back and answer the questions that must be answered in order to advise. A person taking Depakote is likely to be taking this medication following an unsuccessful trial on another medication with greater potential for bone marrow supression. It's greater potential is for liver dysfunction and related hematologic consequences. That warning is clearly labled on the box. Until more is known, this cannot be answered.
 

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