Classification of care persons
To answer the question of whether the nurses are subject to withholding as employees:
The IRS has not been consistent in its treatment of nurses engaged in private-duty work. For example, a National Technical Advice Memorandum issued as IRS Letter Ruling 9123005, dealt with a quadriplegic who hired a licensed practical nurse to perform the following duties: bathing, feeding, exercising, taking vital signs, personal hygiene, household chores, such as laundry, and tracking the patient's physical condition. The IRS said the nurse was performing domestic services as an employee
By contrast, in IRS Letter Ruling 9243016, a family hired two RNs and a LPN to care round the clock for a bedridden parent. The nurses were given written instructions and supplies, and the family had the right to change their methods as they saw fit. The IRS ruled that all of the workers were independent contractors, even though their duties appeared to be overwhelmingly domestic in nature. The ruling says the nurses were responsible for bathing, tube feeding, laundry, emotional and physical support, administering medicine, monitoring vital signs, and keeping the apartment clean.
Therefore, it is not certain how the IRS would classify your nurses. However, in either case, you are OK. If they are self-employed (independent contractors), you don’t have to withhold. On the other hand, if you are classified as household workers, you only need to withhold income tax if they ask you to and if you agree to do it. (IRS Publication 505)